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Article

Differential protection of neuromuscular sensory and motor axons and their endings in Wld(S) mutant mice.

Neuroscience - 3 Jan 2012

Oyebode O R O, Hartley R, Singhota J, Thomson D, Ribchester R R

Abstract excerpt

Orthograde Wallerian degeneration normally brings about fragmentation of peripheral nerve axons and their sensory or motor endings within 24-48 h in mice. However, neuronal expression of the chimaeric, Wld(S) gene mutation extends survival of functioning axons and their distal endings for up to 3 weeks after nerve section. Here we studied the pattern and rate of degeneration of sensory axons and their...

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Identifiers

PMID: 22062136
DOI: 10.1016/j.neuroscience.2011.10.020

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CFP

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Related research

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Differential protection of neuromuscular sensory and motor axons and their endings in Wld(S) mutant mice.PMID 22062136Read ↗

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