Article
Motor neuron death induced by axotomy in neonatal mice occurs more slowly in a mutant strain in which Wallerian degeneration is very slow.
The European journal of neuroscience - 1 Mar 1994
Lapper S R, Brown M C, Perry V H
Abstract excerpt
In contrast to motor neurons of adults, motor neurons of neonatal mice die if their axons are cut. We have examined the extent, the time course and the loss of susceptibility with age to such induced death in C57BL/Wlds mice. This is a strain which has a dominant autosomal mutation which dramatic...
Topics
- Aging
- Animals
- Animals, Newborn
- Axons
- Cell Death
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Motor Neurons
- Mutation
- Reaction Time
- Wallerian Degeneration