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Article

alpha-Synuclein maps to a quantitative trait locus for alcohol preference and is differentially expressed in alcohol-preferring and -nonpreferring rats.

Proceedings of the National Academy of Sciences of the United States of America - 15 Apr 2003

Liang Tiebing, Spence John, Liu Lixiang, Strother Wendy N, Chang Hwai Wen, Ellison Julie A, Lumeng Lawrence, Li Ting-Kai, Foroud Tatiana, Carr Lucinda G

Abstract excerpt

Total gene expression analysis (TOGA) was used to identify genes that are differentially expressed in brain regions between the alcohol-naive, inbred alcohol-preferring (iP), and -nonpreferring (iNP) rats. alpha-Synuclein, expressed at >2-fold higher levels in the hippocampus of the iP than the iNP rat, was prioritized for further study. In situ hybridization was used to determine specific brain regions and cells...

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Identifiers

PMID: 12665621
DOI: 10.1073/pnas.0737182100
PMCID: PMC153617

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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