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Article

Ethanol (EtOH)-Related Behaviors in α-Synuclein Mutant Mice and Association of SNCA SNPs with Anxiety in EtOH-Dependent Patients.

Alcoholism, clinical and experimental research - 1 Nov 2018

Persyn Wolfgang, Houchi Hakim, Papillon Charles-Antoine, Martinetti Margaret, Antol Johann, Guillaumont Cyrille, Dervaux Alain, Naassila Mickael

Abstract excerpt

BACKGROUND: Data have shown a role of α-synuclein in anxiety and also in addiction, particularly in alcohol use disorders (AUD). Since the comorbidity between AUD and anxiety is very high and because anxiety is an important factor in ethanol (EtOH) relapse, the aim of the present study was to investigate the role of α-synuclein in moderating EtOH intake, the anxiolytic effects of EtOH, and EtOH withdrawal-induced...

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Source

Identifiers

PMID: 30120834
DOI: 10.1111/acer.13875

Genes

SNCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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