Article
Identification of candidate genes for alcohol preference by expression profiling of congenic rat strains.
Alcoholism, clinical and experimental research - 1 Jul 2007
Carr Lucinda G, Kimpel Mark W, Liang Tiebing, McClintick Jeanette N, McCall Kevin, Morse Melissa, Edenberg Howard J
Abstract excerpt
BACKGROUND: A highly significant quantitative trait locus (QTL) on chromosome 4 that influenced alcohol preference was identified by analyzing crosses between the iP and iNP rats. Congenic strains in which the iP chromosome 4 QTL interval was transferred to the iNP (NP.P) exhibited the expected increase in alcohol consumption compared with the iNP background strain. This study was undertaken to identify genes in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
