Article
Regulation of alpha-synuclein expression in alcohol-preferring and -non preferring rats.
Journal of neurochemistry - 1 Oct 2006
Liang Tiebing, Carr Lucinda G
Abstract excerpt
The alpha-synuclein (Snca) gene is expressed at higher levels in alcohol-naïve, inbred alcohol-preferring (iP) rats than in alcohol-non preferring (iNP) rats. Snca modulates dopamine transmission and the dopamineregic system, which play a role in mediating the rewarding properties of alcohol consumption. Thus, understanding regulation of Snca gene expression could provide insight into the relationship of Snca and...
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