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Article

Enhanced motivation to alcohol in transgenic mice expressing human α-synuclein.

Journal of neurochemistry - 1 Nov 2017

Rotermund Carola, Reolon Gustavo K, Leixner Sarah, Boden Cindy, Bilbao Ainhoa, Kahle Philipp J

Abstract excerpt

α-Synuclein (αSYN) is the neuropathological hallmark protein of Parkinson's disease (PD) and related neurodegenerative disorders. Moreover, the gene encoding αSYN (SNCA) is a major genetic contributor to PD. Interestingly, independent genome-wide association studies also identified SNCA as the most important candidate gene for alcoholism. Furthermore, single-nucleotide-polymorphisms have been associated with...

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Identifiers

PMID: 28833174
DOI: 10.1111/jnc.14151

Genes

SNCA

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