Article
Evidence for asthma susceptibility genes on chromosome 11 in an African-American population.
Human genetics - 1 Jul 2003
Huang Shau-Ku, Mathias Rasika A, Ehrlich Eva, Plunkett Beverly, Liu Xin, Cutting Garry R, Wang Xin-Jing, Li Xiao-Dong, Togias Alkis, Barnes Kathleen C, Malveaux Floyd, Rich Stephen, Mellen Beverly, Lange Ethan, Beaty Terri H
Abstract excerpt
Initial genome-wide scan data provided suggestive evidence for linkage of the asthma phenotype in African-American (AA), but not Caucasian, families to chromosome 11q markers (peak at D11S1985; LOD=2). To refine this region, mapping analysis of 91 AA families (51 multiplex families and 40 asthmatic case-parent trios) was performed with an additional 17 markers flanking the initial peak linkage marker. Multipoint...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.