Article
A genetic map of chromosome 11q, including the atopy locus.
European journal of human genetics : EJHG - 1 Jan 1995
Sandford A J, Moffatt M F, Daniels S E, Nakamura Y, Lathrop G M, Hopkin J M, Cookson W O
Abstract excerpt
Atopy is a common and genetically heterogeneous syndrome predisposing to allergic asthma and rhinitis. A locus linked to the atopy phenotype has been shown to be present on chromosome 11q12-13. Linkage has only been seen in maternally derived alleles. We have constructed a genetic linkage map of the region, using 15 markers to span approximately 27 cM, and integrate previously published maps. Under a model of...
Topics
- Alleles
- Chromosome Mapping
- Chromosomes, Human, Pair 11
- Cosmids
- Female
- Genetic Linkage
- Genetic Markers
- Humans
- Hypersensitivity, Immediate
- Male
- Minisatellite Repeats
