Article
African Americans with asthma: genetic insights.
Proceedings of the American Thoracic Society - 1 Jan 2007
Barnes Kathleen C, Grant Audrey V, Hansel Nadia N, Gao Peisong, Dunston Georgia M
Abstract excerpt
It has been well established that genetic factors strongly affect susceptibility to asthma and its associated traits. It is less clear to what extent genetic variation contributes to the ethnic disparities observed for asthma morbidity and mortality. Individuals of African descent with asthma have more severe asthma, higher IgE levels, a higher degree of steroid dependency, and more severe clinical symptoms than...
Topics
- Black or African American
- Asthma
- Haplotypes
- Humans
- Linkage Disequilibrium
- Polymorphism, Single Nucleotide