Article
Transferability of genome-wide associated loci for asthma in African Americans.
The Journal of asthma : official journal of the Association for the Care of Asthma - 2 Jan 2017
Faruque Mezbah U, Chen Guanjie, Doumatey Ayo P, Zhou Jie, Huang Hanxia, Shriner Daniel, Adeyemo Adebowale A, Rotimi Charles N, Dunston Georgia M
Abstract excerpt
OBJECTIVE: Transferability of significantly associated loci or GWAS "hits" adds credibility to genotype-disease associations and provides evidence for generalizability across different ancestral populations. We sought evidence of association of known asthma-associated single nucleotide polymorphisms (SNPs) in an African American population. METHODS: Subjects comprised 661 participants (261 asthma cases and 400...
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