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Article

A genome-wide search for asthma susceptibility loci in ethnically diverse populations.

Nature genetics - 1 Apr 1997

Abstract excerpt

Asthma is an inflammatory airways disease associated with intermittent respiratory symptoms, bronchial hyper-responsiveness (BHR) and reversible airflow obstruction and is phenotypically heterogeneous. Patterns of clustering and segregation analyses in asthma families have suggested a genetic component to asthma. Previous studies reported linkage of BHR and atopy to chromosomes 5q (refs 7-9), 6p (refs 10-12), 11q...

Topics

Asthma
Black People
Chromosome Mapping
Disease Susceptibility
Genome, Human
Genotype
Hispanic or Latino
Humans
Lod Score
Nuclear Family
White People
Black or African American

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9090385
DOI: 10.1038/ng0497-389

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A genome-wide search for asthma susceptibility loci in ethnically diverse populations.PMID 9090385Read ↗

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Susceptibility genes in asthma and allergy.Semantic proximity Read ↗

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Significant evidence for linkage to chromosome 5q13 in a genome-wide scan for asthma in an extended pedigree resource.Semantic proximity Read ↗

A large-scale, consortium-based genomewide association study of asthma.Semantic proximity Read ↗

Phenotypic and genetic heterogeneity in a genome-wide linkage study of asthma families.Semantic proximity Read ↗

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