Article
Expression quantitative trait locus fine mapping of the 17q12-21 asthma locus in African American children: a genetic association and gene expression study.
The Lancet. Respiratory medicine - 1 May 2020
Ober Carole, McKennan Chris G, Magnaye Kevin M, Altman Matthew C, Washington Charles, Stanhope Catherine, Naughton Katherine A, Rosasco Mario G, Bacharier Leonard B, Billheimer Dean, Gold Diane R, Gress Lisa, Hartert Tina, Havstad Suzanne, Khurana Hershey Gurjit K, Hallmark Brian, Hogarth D Kyle, Jackson Daniel J, Johnson Christine C, Kattan Meyer, Lemanske Robert F, Lynch Susan V, Mendonca Eneida A, Miller Rachel L, Naureckas Edward T, O'Connor George T, Seroogy Christine M, Wegienka Ganesa, White Steven R, Wood Robert A, Wright Anne L, Zoratti Edward M, Martinez Fernando D, Ownby Dennis, Nicolae Dan L, Levin Albert M, Gern James E
Abstract excerpt
BACKGROUND: African ancestry is associated with a higher prevalence and greater severity of asthma than European ancestries, yet genetic studies of the most common locus associated with childhood-onset asthma, 17q12-21, in African Americans have been inconclusive. The aim of this study was to leverage both the phenotyping of the Children's Respiratory and Environmental Workgroup (CREW) birth cohort consortium,...
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