Article
Genetic architecture of asthma in African American patients.
The Journal of allergy and clinical immunology - 1 Apr 2023
Chang Xiao, March Michael, Mentch Frank, Qu Huiqi, Liu Yichuan, Glessner Joseph, Sleiman Patrick, Hakonarson Hakon
Abstract excerpt
BACKGROUND: Asthma is a chronic inflammatory disorder with a strong genetic inheritance. Although more than 100 loci were reported through the genome-wide association study of European populations, the genetic underpinning of asthma in African American individuals remains largely elusive. OBJECTIVE: We aimed to identify genetic loci associated with asthma in African American individuals. METHODS: Three cohorts...
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