Article
Genomewide screen and identification of gene-gene interactions for asthma-susceptibility loci in three U.S. populations: collaborative study on the genetics of asthma.
American journal of human genetics - 1 Jun 2001
Xu J, Meyers D A, Ober C, Blumenthal M N, Mellen B, Barnes K C, King R A, Lester L A, Howard T D, Solway J, Langefeld C D, Beaty T H, Rich S S, Bleecker E R, Cox N J
Abstract excerpt
The genomewide screen to search for asthma-susceptibility loci, in the Collaborative Study on the Genetics of Asthma (CSGA), has been conducted in two stages and includes 266 families (199 nuclear and 67 extended pedigrees) from three U.S. populations: African American, European American, and Hispanic. Evidence for linkage with the asthma phenotype was observed for multiple chromosomal regions, through use of...
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