On the power to detect SNP/phenotype association in candidate quantitative trait loci genomic regions: a simulation study.

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Article

On the power to detect SNP/phenotype association in candidate quantitative trait loci genomic regions: a simulation study.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2003

Comeron Josep M, Kreitman Martin, De La Vega Francisco M

Abstract excerpt

We use coalescent methods to investigate the ability of linked neutral "markers" to reveal in simulated population samples the presence of one or more single nucleotide polymorphisms that is contributing to a trait having a complex genetic basis (QTN: quantitative trait nucleotide). Realistic mut...

Topics

Computational Biology
Diploidy
Genetic Variation
Genetics, Population
Humans
Models, Genetic
Mutation
Phenotype
Polymorphism, Single Nucleotide
Probability
Quantitative Trait Loci
Recombination, Genetic

Source

Open in PubMed

Identifiers

PMID: 12603051

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-12603051-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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