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Article

On the power to detect SNP/phenotype association in candidate quantitative trait loci genomic regions: a simulation study.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2003

Comeron Josep M, Kreitman Martin, De La Vega Francisco M

Abstract excerpt

We use coalescent methods to investigate the ability of linked neutral "markers" to reveal in simulated population samples the presence of one or more single nucleotide polymorphisms that is contributing to a trait having a complex genetic basis (QTN: quantitative trait nucleotide). Realistic mutation and recombination rates in our simulations allow us to generate SNP data appropriate for analyzing human...

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PMID: 12603051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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