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Article

Locating human quantitative trait loci: guidelines for the selection of sibling pairs for genotyping.

Behavior genetics - 1 Sept 1994

Eaves L, Meyer J

Abstract excerpt

Simulation studies were conducted to assess the relative merits of different nonrandom sampling strategies for the selection of sibling pairs for genotyping in the attempt to locate individual loci (QTLs) contributing to variation in human quantitative traits. For a constant amount of variation contributed by a QTL (25% of the total) the frequencies and dominance relationships of a trait increasing allele were...

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PMID: 7993321
DOI: 10.1007/BF01076180

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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