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Article

A coalescent approach to study linkage disequilibrium between single-nucleotide polymorphisms.

American journal of human genetics - 1 Feb 2000

Zöllner S, von Haeseler A

Abstract excerpt

We present the results of extensive simulations that emulate the development and distribution of linkage disequilibrium (LD) between single-nucleotide polymorphisms (SNPs) and a gene locus that is phenotypically stratified into two classes (disease phenotype and wild-type phenotype). Our approach, based on coalescence theory, allows an explicit modeling of the demographic history of the population without...

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Identifiers

PMID: 10677321
DOI: 10.1086/302766
PMCID: PMC1288114

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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