Article
Does haplotype diversity predict power for association mapping of disease susceptibility?
Human genetics - 1 Jul 2004
Zhang Weihua, Collins Andrew, Morton Newton E
Abstract excerpt
Many recent studies have established that haplotype diversity in a small region may not be greatly diminished when the number of markers is reduced to a smaller set of "haplotype-tagging" single-nucleotide polymorphisms (SNPs) that identify the most common haplotypes. These studies are motivated by the assumption that retention of haplotype diversity assures retention of power for mapping disease susceptibility...
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