Article
Prospects for whole-genome linkage disequilibrium mapping of common disease genes.
Nature genetics - 1 Jun 1999
Kruglyak L
Abstract excerpt
Recently, attention has focused on the use of whole-genome linkage disequilibrium (LD) studies to map common disease genes. Such studies would employ a dense map of single nucleotide polymorphisms (SNPs) to detect association between a marker and disease. Construction of SNP maps is currently underway. An essential issue yet to be settled is the required marker density of such maps. Here, I use population...
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