Article
The value of molecular haplotypes in a family-based linkage study.
American journal of human genetics - 1 Sept 2006
Gillanders E M, Pearson J V, Sorant A J M, Trent J M, O'Connell J R, Bailey-Wilson J E
Abstract excerpt
Novel methods that could improve the power of conventional methods of gene discovery for complex diseases should be investigated. In a simulation study, we aimed to investigate the value of molecular haplotypes in the context of a family-based linkage study. The term "haplotype" (or "haploid genotype") refers to syntenic alleles inherited on a single chromosome, and we use the term "molecular haplotype" to refer...
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