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Article

Engineering the metabolism of Escherichia coli W3110 for the conversion of sugar to redox-neutral and oxidized products: homoacetate production.

Proceedings of the National Academy of Sciences of the United States of America - 4 Feb 2003

Causey T B, Zhou S, Shanmugam K T, Ingram L O

Abstract excerpt

Microbial processes for commodity chemicals have focused on reduced products and anaerobic conditions where substrate loss to cell mass and CO(2) are minimal and product yields are high. To facilitate expansion into more oxidized chemicals, Escherichia coli W3110 was genetically engineered for acetate production by using an approach that combines attributes of fermentative and oxidative metabolism (rapid growth,...

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Identifiers

PMID: 12556564
DOI: 10.1073/pnas.0337684100
PMCID: PMC298686

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Source receipt: pubmed, retrieved 7 Sept 2026.

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