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High-yield anaerobic succinate production by strategically regulating multiple metabolic pathways based on stoichiometric maximum in Escherichia coli.

Microbial cell factories - 12 Aug 2016

Meng Jiao, Wang Baiyun, Liu Dingyu, Chen Tao, Wang Zhiwen, Zhao Xueming

Abstract excerpt

BACKGROUND: Succinate has been identified by the U.S. Department of Energy as one of the top 12 building block chemicals, which can be used as a specialty chemical in the agricultural, food, and pharmaceutical industries. Escherichia coli are now one of the most important succinate producing candidates. However, the stoichiometric maximum succinate yield under anaerobic conditions through the reductive branch of...

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Identifiers

PMID: 27520031
DOI: 10.1186/s12934-016-0536-1
PMCID: PMC4983090

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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