Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Model-aided atpE gene knockout strategy in Escherichia coli for enhanced succinic acid production from glycerol.

Journal of biomolecular structure & dynamics - 1 Aug 2016

Mienda Bashir Sajo, Shamsir Mohd Shahir, Md Illias Rosli

Abstract excerpt

Succinic acid is an important platform chemical with a variety of applications. Model-guided metabolic engineering strategies in Escherichia coli for strain improvement to increase succinic acid production using glucose and glycerol remain largely unexplored. Herein, we report what are, to our knowledge, the first metabolic knockout of the atpE gene to have increased succinic acid production using both glucose...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Escherichia coli Proteins
Share to Fermentation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Knockout Techniques

Share to Glucose

Share to Glycerol

Share to Metabolic Networks and Pathways

Share to Models, Biological

Share to Succinic Acid

Source

Identifiers

PMID: 26513379
DOI: 10.1080/07391102.2015.1090341

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Model-aided atpE gene knockout strategy in Escherichia coli for enhanced succinic acid production from glycerol.PMID 26513379Read ↗

Escherichia coli genome-scale metabolic gene knockout of lactate dehydrogenase (ldhA), increases succinate production from glycerol.Semantic proximity Read ↗

Directed pathway evolution of the glyoxylate shunt in Escherichia coli for improved aerobic succinate production from glycerol.Semantic proximity Read ↗

High-yield anaerobic succinate production by strategically regulating multiple metabolic pathways based on stoichiometric maximum in Escherichia coli.Semantic proximity Read ↗

Metabolic engineering of Escherichia coli and in silico comparing of carboxylation pathways for high succinate productivity under aerobic conditions.Semantic proximity Read ↗

Industrial systems biology of Saccharomyces cerevisiae enables novel succinic acid cell factory.Semantic proximity Read ↗

Chemostat culture characterization of Escherichia coli mutant strains metabolically engineered for aerobic succinate production: a study of the modified metabolic network based on metabolite profile, enzyme activity, and gene expression profile.Semantic proximity Read ↗

Engineering Escherichia coli for fumaric acid production from glycerol.Semantic proximity Read ↗

Enhanced succinic acid production under acidic conditions by introduction of glutamate decarboxylase system in E. coli AFP111.Semantic proximity Read ↗

Identification of Enzymatic Bottlenecks for the Aerobic Production of Malate from Glycerol by the Systematic Gene Overexpression of Anaplerotic Enzymes in Escherichia coli.Semantic proximity Read ↗

A systematic analysis of TCA Escherichia coli mutants reveals suitable genetic backgrounds for enhanced hydrogen and ethanol production using glycerol as main carbon source.Semantic proximity Read ↗

Enhanced succinic acid production by Actinobacillus succinogenes after genome shuffling.Semantic proximity Read ↗

Comparative fluxome and metabolome analysis for overproduction of succinate in Escherichia coli.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.