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Article

Body size, insulin/IGF signaling and aging in the nematode Caenorhabditis elegans.

Experimental gerontology - 1 Jan 2000

McCulloch Diana, Gems David

Abstract excerpt

A number of recent studies of aging in Drosophila, mice and dogs have shown an association between reduced body size and increased lifespan. It is unclear (a) whether such an association is a general feature of animal species; and (b) whether the association reflects an effect of body size on aging, or pleiotropic effects of common determinants of growth and aging. To address these issues, we have studied the...

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PMID: 12543270
DOI: 10.1016/s0531-5565(02)00147-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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