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Article

Genetics, life span, health span, and the aging process in Caenorhabditis elegans.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 May 2012

Tissenbaum Heidi A

Abstract excerpt

As a tool for measuring the aging process, life span has been invaluable in dissecting the genes that modulate longevity. Studies over the past few decades have identified several hundred genes that can modify life span in model organisms such as yeast, worms, and flies. Yet, despite this vast amount of research, we still do not fully understand how the genes that affect life span influence how an organism ages....

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Identifiers

PMID: 22499764
DOI: 10.1093/gerona/gls088
PMCID: PMC3410663

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