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The role of insulin/IGF-like signaling in C. elegans longevity and aging

31 Mar 2010

Abstract excerpt

Aging is characterized by general physiological decline over time. A hallmark of human senescence is the onset of various age-related afflictions including neurodegeneration, cardiovascular disease and cancer. Although environmental and stochastic factors undoubtedly contribute to the increased incidence of disease with age, recent studies suggest that intrinsic genetic determinants govern both life span and...

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PMID: 20354111
DOI: 10.1242/dmm.001040

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