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Article

Characterization of a highly attenuated Salmonella enterica serovar Typhimurium mutant strain.

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi - 1 Dec 2002

Tang Ing-Kae, Ji Dar-Der, Chou Chi-Fu, Lin Hung-Chi, Liao Chin-Len, Sytwu Huey-Kang, Wang Jaang-Jiun, Liu Yu-Tien

Abstract excerpt

Salmonella enterica serovar Typhimurium ATCC 13311 is virulent at a dose as low as 10(2) colony-forming units when administered intraperitoneally to BALB/c mice. In order to develop highly attenuated mutant strain through the combination of 2 phenotypically attenuated markers, we constructed a number of amino acid requiring auxotrophic strains of S. enterica serovar Typhimurium by means of UV-induced mutations....

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PMID: 12542248

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