Article
Changes of physiological and biochemical properties of Salmonella enterica serovar Typhimurium by deletion of cpxR and lon genes using allelic exchange method.
Journal of microbiological methods - 1 Dec 2009
Kim Sam Woong, Moon Ki Hwan, Baik Hyung Suk, Kang Ho Young, Kim Sung Koo, Bahk Jeong Dong, Hur Jin, Lee John Hwa
Abstract excerpt
To construct a novel Salmonella attenuated live vaccine, the cpxR and lon genes were deleted from a wild-type Salmonella enterica serovar Typhimurium (S. Typhimurium) using allelic exchange method, resulting in S. Typhimurium CK31 (DeltacpxR), CK38 (Deltalon), and CK111 (DeltacpxR/lon). These mut...
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