Article
DNA methylation modulates Salmonella enterica serovar Typhimurium virulence in Caenorhabditis elegans.
FEMS microbiology letters - 1 Apr 2005
Oza Javin P, Yeh Jimmy B, Reich Norbert O
Abstract excerpt
Salmonella enterica serovar Typhimurium was previously shown to be virulent in Caenorhabditis elegans. Here we demonstrate that DNA adenine methyltransferase (DAM) modulates Salmonella virulence in the nematode, as it does in mice. After 5 days of continual exposure to bacteria, twice as many worms died when exposed to the wild-type than the dam-mutant strain of Salmonella. Similar trends in virulence were...
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