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Article

Attenuated mutants of Salmonella enterica Typhimurium mediate melanoma regression via an immune response.

Experimental biology and medicine (Maywood, N.J.) - 1 Jan 2024

Pérez Jorge Genesy, Gontijo Marco, Silva Marina Flóro E, Goes Isabella Carolina Rodrigues Dos Santos, Jaimes-Florez Yessica Paola, Coser Lilian de Oliveira, Rocha Francisca Janaína Soares, Giorgio Selma, Brocchi Marcelo

Abstract excerpt

The lack of effective treatment options for an increasing number of cancer cases highlights the need for new anticancer therapeutic strategies. Immunotherapy mediated by Salmonella enterica Typhimurium is a promising anticancer treatment. Candidate strains for anticancer therapy must be attenuated while retaining their antitumor activity. Here, we investigated the attenuation and antitumor efficacy of two S....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38974834
DOI: 10.3389/ebm.2024.10081
PMCID: PMC11224151

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