Article
Genetic polymorphism of interleukin-10 (-A592C) among oral cancer with squamous cell carcinoma.
Archives of oral biology - 1 May 2017
Singh Prithvi Kumar, Ahmad Mohammad Kaleem, Kumar Vijay, Gupta Rajni, Kohli Monica, Jain Amita, Mahdi Abbas Ali, Bogra Jaishri, Chandra Girish
Abstract excerpt
OBJECTIVE: Interleukin-10 (IL-10) is a pleiotropic cytokine with either immunosuppressive or immunostimulative activities. It has been reported that in cancer, the promoter region polymorphism of IL-10 (-A592C) alters both the expression and serum levels of this cytokine. In the present study, we have addressed the question as to whether the single nucleotide polymorphisms (SNPs) at positions -592 A/C in the...
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