Article
Genetic variations of IL-10: Identification of novel variations and evaluation of the impact of the SNPs/haplotype in the promoter region with the progression of Oral Squamous Cell Carcinoma in Indian population.
Cytokine - 1 Mar 2018
Sharma Upma, Singhal Pallavi, Bandil Kapil, Kumar Anoop, Bose Surojit, Ahuja Puneet, Kohli Molushree, Dewan Ajay Kumar, Tayal Juhi, Banerjee Basu Dev, Prasheri Aditya, Mehrotra Ravi, Sharma Veena, Bharadwaj Mausumi
Abstract excerpt
The correlation of interleukin 10 (IL-10) with the outbreak and progression of cancer has been well established as it contributes to tumor immune evasion. Convincing number of evidences has been accumulated to reflect the critical correlation between IL-10 polymorphism and tumorogenesis. Several polymorphic sites at promoter regions have been reported to be associated with cancer susceptibility. The purpose of...
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