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Association study indicates combined effect of interleukin-10 and angiotensin-converting enzyme in basal cell carcinoma development.

Archives of dermatological research - 1 Jul 2021

Koronellos Nikolaos, Yapijakis Christos, Katoulis Alexandros, Avgoustidis Dimitris, Vylliotis Antonis, Papakosta Veronica, Diamantopoulou Stavroula, Zografos Omiros, Vairaktari Georgia, Vairaktaris Eleftherios, Vassiliou Stavros

Abstract excerpt

Cytokines involved in inflammatory and immune response have been associated with risk for development of basal cell carcinoma (BCC). In this study, three functional DNA polymorphisms affecting gene expression were investigated in 54 BCC patients and 111 healthy controls: interleukin-1b (IL-1b) +3953C/T, interleukin-10 (IL-10) - 1082G/A and angiotensin-converting enzyme (ACE) insertion/deletion (I/D)...

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Angiotensins
Biomarkers, Tumor
Carcinoma, Basal Cell
Gene Expression Regulation, Neoplastic

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PMID: 32772162
DOI: 10.1007/s00403-020-02113-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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