Article
Polymorphisms of the interleukin 10 gene promoter in patients from Brazil with epidermodysplasia verruciformis.
Journal of the American Academy of Dermatology - 1 Oct 2003
de Oliveira Walmar Roncalli P, Rady Peter L, Grady James, Hughes Thomas K, Festa Neto Cyro, Rivitti Evandro A, Tyring Stephen K
Abstract excerpt
BACKGROUND: Epidermodysplasia verruciformis (EV) is a rare genetic disorder characterized by development of lesions associated with human papillomavirus in early childhood and malignant transformation in approximately half of individuals during adulthood. The persistence of human papillomavirus infection in EV is thought to be a result of an immunogenetic defect, which determines the generation of several...
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