Article
In silico quantitative trait locus map for atherosclerosis susceptibility in apolipoprotein E-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jan 2003
Smith Jonathan D, James Daylon, Dansky Hayes M, Wittkowski Knut M, Moore Karen J, Breslow Jan L
Abstract excerpt
OBJECTIVE: Atherosclerosis susceptibility is a genetic trait that varies between mouse strains. The goal of this study was to use a public mouse single nucleotide polymorphism (SNP) database to define the genetic loci that are associated with this trait, without the need to perform strain intercrosses that are normally required to obtain these loci. METHODS AND RESULTS: Apolipoprotein E (apoE)-deficient mice on 6...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
