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Article

Genetic and comparative mapping of genes dysregulated in mouse hearts lacking the Hand2 transcription factor gene.

Genomics - 1 Dec 2002

Villanueva Melissa P, Aiyer Aparna R, Muller Shaine, Pletcher Mathew T, Liu Xiao, Emanuel Beverly, Srivastava Deepak, Reeves Roger H

Abstract excerpt

The helix-loop-helix transcription factor HAND2 plays a vital role in the development of the heart, limb, facies, and other neural crest-derived structures. We used differential display analysis to identify 33 putative HAND2-regulated ESTs that are differentially expressed in Hand2(-/-) vs wild-type mice. We determined the positions on mouse and human genetic maps of 29 of these by using the T31 mouse Radiation...

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Source

Identifiers

PMID: 12504851
DOI: 10.1006/geno.2002.7009

Genes

HAND2

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Source receipt: pubmed, retrieved 7 Sept 2026.

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