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Article

Characterization of deleterious mutations in outcrossing populations.

Genetics - 1 Oct 1998

Deng H W

Abstract excerpt

Deng and Lynch recently proposed estimating the rate and effects of deleterious genomic mutations from changes in the mean and genetic variance of fitness upon selfing/outcrossing in outcrossing/highly selfing populations. The utility of our original estimation approach is limited in outcrossing populations, since selfing may not always be feasible. Here we extend the approach to any form of inbreeding in...

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Identifiers

PMID: 9755222
DOI: 10.1093/genetics/150.2.945
PMCID: PMC1460375

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