Article
Analysis and implications of mutational variation.
Genetica - 1 Jun 2009
Keightley Peter D, Halligan Daniel L
Abstract excerpt
Variation from new mutations is important for several questions in quantitative genetics. Key parameters are the genomic mutation rate and the distribution of effects of mutations (DEM), which determine the amount of new quantitative variation that arises per generation from mutation (V(M)). Here, we review methods and empirical results concerning mutation accumulation (MA) experiments that have shed light on...
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