Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Estimation of the rate and effects of deleterious genomic mutations in finite populations with linkage disequilibrium.

Heredity - 1 Jul 2005

Li J, Deng H-W

Abstract excerpt

Under several assumptions such as infinite population size with unlinked loci at linkage equilibrium (LD) under mutation-selection (M-S) balance, the rate (U), and the average effects (dominance and selection coefficients h and s) of deleterious genomic mutations (DGM) can be estimated by the Deng-Lynch method in some natural populations. However, all natural populations are finite in size and many of them are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetics, Population
Share to Linkage Disequilibrium
Share to Models, Genetic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Population Density

Share to Population Dynamics

Share to Reproducibility of Results

Source

Identifiers

PMID: 15931248
DOI: 10.1038/sj.hdy.6800689

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Estimation of the rate and effects of deleterious genomic mutations in finite populations with linkage disequilibrium.PMID 15931248Read ↗

Estimation of parameters of deleterious mutations in partial selfing or partial outcrossing populations and in nonequilibrium populations.Semantic proximity Read ↗

Estimation of deleterious genomic mutation parameters in natural populations by accounting for variable mutation effects across loci.Semantic proximity Read ↗

Characterization of deleterious mutations in outcrossing populations.Semantic proximity Read ↗

On the three methods for estimating deleterious genomic mutation parameters.Semantic proximity Read ↗

Direct estimation of per nucleotide and genomic deleterious mutation rates in Drosophila.Semantic proximity Read ↗

The effect of overdominance on characterizing deleterious mutations in large natural populations.Semantic proximity Read ↗

Analysis of the biases in the estimation of deleterious mutation parameters from natural populations at mutation-selection balance.Semantic proximity Read ↗

From Drift to Draft: How Much Do Beneficial Mutations Actually Contribute to Predictions of Ohta's Slightly Deleterious Model of Molecular Evolution?Semantic proximity Read ↗

Upper limit of the rate and per generation effects of deleterious genomic mutations.Semantic proximity Read ↗

Inbreeding depression and inferred deleterious-mutation parameters in Daphnia.Semantic proximity Read ↗

Estimation of the upper limit of the mutation rate and mean heterozygous effect of deleterious mutations.Semantic proximity Read ↗

Inbreeding depression due to mildly deleterious mutations in finite populations: size does matter.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.