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Article

Regulation of Easter activity is required for shaping the Dorsal gradient in the Drosophila embryo.

Development (Cambridge, England) - 1 Dec 2002

Chang Andy J, Morisato Donald

Abstract excerpt

Dorsoventral polarity of the Drosophila embryo requires maternal spätzle-Toll signaling to establish a nuclear gradient of Dorsal protein. The shape of this gradient is altered in embryos produced by females carrying dominant alleles of easter (ea(D)). The easter gene encodes a serine protease that generates processed Spätzle, which is proposed to act as the Toll ligand. By examining the expression domains of the...

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PMID: 12421704
DOI: 10.1242/dev.00161

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Regulation of Easter activity is required for shaping the Dorsal gradient in the Drosophila embryo.PMID 12421704Read ↗

Dominant and recessive alleles of the Drosophila easter gene are point mutations at conserved sites in the serine protease catalytic domain.Semantic proximity Read ↗

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