Article
Dominant and recessive alleles of the Drosophila easter gene are point mutations at conserved sites in the serine protease catalytic domain.
Cell - 9 Mar 1990
Jin Y S, Anderson K V
Abstract excerpt
The easter gene, required for the development of all lateral and ventral pattern elements in the Drosophila embryo, appears to encode an extracellular serine protease. Dominant easter alleles increase the number of cells that give rise to lateral and ventral structures. We have found that nine do...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Binding Sites
- Cattle
- DNA
- Drosophila melanogaster
- Female
- Genes
- Genes, Dominant
- Genes, Recessive
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Oligonucleotide Probes
- Polymerase Chain Reaction
- Protein Conformation
- Restriction Mapping