Article
Multiple isoforms of the Drosophila Spätzle protein are encoded by alternatively spliced maternal mRNAs in the precellular blastoderm embryo.
Molecular & general genetics : MGG - 1 Jan 2001
DeLotto Y, Smith C, DeLotto R
Abstract excerpt
The spätzle gene is required for proper specification of positional information along the dorsal-ventral axis of the Drosophila embryo and for induction of the innate immune response to fungal infection. It has been shown to encode a precursor of a Nerve Growth Factor-like ligand which is also a member of the cysknot protein superfamily. In dorsal-ventral patterning, the most widely accepted model of the pathway...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.