Article
Dominant and recessive mutations define functional domains of Toll, a transmembrane protein required for dorsal-ventral polarity in the Drosophila embryo.
Genes & development - 1 May 1991
Schneider D S, Hudson K L, Lin T Y, Anderson K V
Abstract excerpt
The asymmetry of the dorsal-ventral pattern of the Drosophila embryo appears to depend on the ventral activation of the transmembrane Toll protein. The Toll protein is found around the entire dorsal-ventral circumference of the embryo, and it appears to act as a receptor for a ventral, extracellu...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Drosophila
- Drosophila Proteins
- Genes, Dominant
- Genes, Recessive
- Humans
- Insect Hormones
- Membrane Proteins
- Molecular Sequence Data
- Mutation
- Phenotype
- Receptors, Cell Surface
- Receptors, Immunologic
- Receptors, Interleukin-1
- Sequence Homology, Nucleic Acid
- Signal Transduction