Article
The Toll pathway is required in the epidermis for muscle development in the Drosophila embryo.
Developmental biology - 1 Jul 1998
Halfon M S, Keshishian H
Abstract excerpt
The Toll signaling pathway functions in several Drosophila processes, including dorsal-ventral pattern formation and the immune response. Here, we demonstrate that this pathway is required in the epidermis for proper muscle development. Previously, we showed that the zygotic Toll protein is necessary for normal muscle development; in the absence of zygotic Toll, close to 50% of hemisegments have muscle patterning...
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