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Article

Sleep in mice with nonfunctional growth hormone-releasing hormone receptors.

American journal of physiology. Regulatory, integrative and comparative physiology - 1 Jan 2003

Obal Ferenc, Alt Jeremiah, Taishi Ping, Gardi Janos, Krueger James M

Abstract excerpt

The role of the somatotropic axis in sleep regulation was studied by using the lit/lit mouse with nonfunctional growth hormone (GH)-releasing hormone (GHRH) receptors (GHRH-Rs) and control heterozygous C57BL/6J mice, which have a normal phenotype. During the light period, the lit/lit mice displayed significantly less spontaneous rapid eye movement sleep (REMS) and non-REMS (NREMS) than the controls....

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Source

Identifiers

PMID: 12388430
DOI: 10.1152/ajpregu.00361.2002

Genes

GHRH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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