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Article

Characterization of adult ghrelin and ghrelin receptor knockout mice under positive and negative energy balance.

Endocrinology - 1 Feb 2008

Sun Yuxiang, Butte Nancy F, Garcia Jose M, Smith Roy G

Abstract excerpt

Ghrelin and the ghrelin receptor (GH secretagogue receptor, GHS-R), are believed to have important roles in energy homeostasis. We describe results from the first studies to be conducted in congenic (N10) adult ghrelin(-/-) and Ghsr(-/-) mice under conditions of both positive (high-fat diet) and negative (caloric restriction) energy balance. In contrast to results from young N2 mutant mice, changes in body weight...

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Identifiers

PMID: 18006636
DOI: 10.1210/en.2007-0271
PMCID: PMC2219310

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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