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Article

Behavioural phenotyping of male growth hormone-releasing hormone (GHRH) knockout mice.

Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society - 1 Oct 2014

Leone Sheila, Shohreh Rugia, Manippa Fabio, Recinella Lucia, Ferrante Claudio, Orlando Giustino, Salvatori Roberto, Vacca Michele, Brunetti Luigi

Abstract excerpt

OBJECTIVE: GH-releasing hormone (GHRH) is a key regulator of GH secretion. The role of GH in anxiety is somewhat contradictory. The aim of this study is to elucidate the consequences of lack of GHRH on emotional behaviour in a mouse model of GH deficiency due to removal of the GHRH gene (GHRH knock out, GHRHKO). DESIGN: Homozygous GHRHKO and wild type male mice were utilized for this study. The emotional...

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Source

Identifiers

PMID: 25028079
DOI: 10.1016/j.ghir.2014.06.004

Genes

GHRH
TRH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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