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Article

Trf4 and Trf5 proteins of Saccharomyces cerevisiae exhibit poly(A) RNA polymerase activity but no DNA polymerase activity.

Molecular and cellular biology - 1 Nov 2005

Haracska Lajos, Johnson Robert E, Prakash Louise, Prakash Satya

Abstract excerpt

The Saccharomyces cerevisiae Trf4 and Trf5 proteins are members of a distinct family of eukaryotic DNA polymerase beta-like nucleotidyltransferases, and a template-dependent DNA polymerase activity has been reported for Trf4. To define the nucleotidyltransferase activities associated with Trf4 and Tr5, we purified these proteins from yeast cells and show that whereas both proteins exhibit a robust poly(A)...

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Identifiers

PMID: 16260630
DOI: 10.1128/MCB.25.22.10183-10189.2005
PMCID: PMC1280283

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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