Article
Cid13 is a cytoplasmic poly(A) polymerase that regulates ribonucleotide reductase mRNA.
Cell - 31 May 2002
Saitoh Shigeaki, Chabes Andrei, McDonald W Hayes, Thelander Lars, Yates John R, Russell Paul
Abstract excerpt
Fission yeast Cid13 and budding yeast Trf4/5 are members of a newly identified nucleotidyltransferase family conserved from yeast to man. Trf4/5 are thought to be essential DNA polymerases. We report that Cid13 is a poly(A) polymerase. Unlike conventional poly(A) polymerases, which act in the nucleus and indiscriminately polyadenylate all mRNA, Cid13 is a cytoplasmic enzyme that specifically targets suc22 mRNA...
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